The immune system and idiopathic nephrotic syndrome

RE Campbell, JM Thurman - … Journal of the American Society of …, 2022 - journals.lww.com
Idiopathic nephrotic syndrome often responds to immunosuppressive treatment.
Nevertheless, this syndrome—and the drugs used to treat it—remain important causes of
patient morbidity. Idiopathic nephrotic syndrome is usually caused by minimal change
disease or FSGS, diseases that primarily affect the podocytes. In spite of decades of
research, the underlying causes of both diseases remain incompletely understood. There is,
however, a large body of observational and experimental data linking the immune system …